Hi!
I've studied a little bit the mime types and found the way to associate the different files to UGENE in Ubuntu (I'm using 12.04). Also, I made icons and a script. In order to work, "icons.tar.gz" and "ugene.xml" should be placed in your home folder. The script can be placed anywhere but remember to make it executable (right click/"Properties"/"Permissions"/"Allow executing file as program"). Then double click and choose "Run in terminal".
Currently, the files associated are:
*.fa
*.gb
*.aln
*.uprj
*.uwl
*.uql
Note:
The fasta and genbank icons are modified versions of this one:
http://commons.wikimedia.org/wiki/File:DNA_icon.svgUpdate: forgot to add a key line to the script.